Developmental Biology 2 (2024) Syllabus
発生生物学 2 (2024) シラバス




Course description:
Various developmental events, such as cell fate determination, cell differentiation, morphogenesis and animal behavior will be analyzed in light of gene expression, cell-cell interaction, intracellular signaling and evolution. Classes will be run by critical reading of the primary literature and discussion.

科目の概要:
細胞運命決定、細胞分化、形態形成や個体の行動制御等の個体発生の様々な現象を、遺伝子発現調節、細胞間相互作用、細胞内情報伝達等の分子機構や進化の視点から議論し、論文講読とディスカッションを通した演習を行う。(講義)

Course purpose:
Development can be viewed as an integral of molecular and cell biological events, and also is a process though which evolutionary changes in form is generated. Through discussing how the principles and concepts of developmental biology developed and what kind of new challenges they generate, students are expected to nurture their framework in which they conduct their own work in various disciplines.

科目の目的:
発生現象は分子細胞学的現象が「積分」されたものと捉えることができます。また、発生過程は形態変化の進化がおこる場所でもあります。この授業では、発生生物学の様々な原理や概念がどのようにして生まれ、どのような新たな問題を生み出すかを議論することを通じ、各自が自分の分野での研究の枠組みを作るのに役立ててもらうことを目指しています。

Contents:
This course will introduce basic principles and concepts of that direct developmental phenomena. Various developmental events, such as cell fate determination, cell differentiation, morphogenesis and animal behavior will be analyzed in light of gene expression, cell-cell interaction, intracellular signaling and evolution. Classes will be run by critical reading of the primary literature and discussion. Please download the paper from links below and take a look at it in advance. It is not necessary to have completely understood the paper before coming to class. This course will be conducted in English. For questions and comments in Japanese, lecturers will provide simultaneous translation service to English.

授業内容:
授業計画:この授業では個体発生を指令する様々な基本原理や概念をとりあげます。細胞運命決定、細胞分化、形態変化、行動等のイベントについて、遺伝子発現、細胞間相互作用、シグナル伝達や進化等の観点から分析します。この授業は「原著論文を読んで議論する」という形式で行います。前もって論文を以下のリンクからダウンロードし、目を通しておいてください。完全に理解する必要はありません。この授業は英語で行いますが、日本語での質問やコメントに対しては講師が同時通訳サービスを提供します。

Time: 13:30 - 15:10 on Mondays 月曜13:30-15:10

Place: National Institute of Genetics, B301 (Library 3rd floor seminar room) 遺伝研B301(図書館3階)
People in other programs/institutions can participate in this class through the remote lecture (Zoom).
他コースの方は遠隔講義(Zoom)で受講できます.

Cource organizer: SAWA Hitoshi 澤 斉 Participating faculty 担当教員リスト
Schedule:

Date Lecturers Topic and paper
2024/11/11
SAWA Hitoshi
澤 斉
Cell-cell interaction and asymmetric cell division
2024/11/18
ZHU Yan
Yan Zhu
Collective cell migration
2024/11/25
KURAKU Shigehiro
工樂 樹洋
Genomic encoding of homeotic gene regulation
2024/12/ 2
KOIDE Tsuyoshi
小出 剛
Imprinting on parental genomes
2024/12/ 9
SAITO Kuniaki
齋藤 都暁

Nuage function in germ cell development

2024/12/16 ASAKAWA Kazuhide 
浅川 和秀
Cell size and development
2024/12/23
MATSUMOTO Akihiro
松本 彰弘

Visual neural circuit formation

2025/ 1/ 6
IWASATO Takuji
岩里 琢治
Spontaneous activity in neural circuit development

The reading list and the course schedule is tentative and is subject to change.
使用する論文は変更される可能性があります.
Appropriate grade level and Eligible Programs: (x) 1, (x) 2, (x) 3, (x) 4, (x) 5:
(x) All Programs

Pre-requisites: Familiarity with basic concepts of Molecular and Cell Biology is recommended.
This course will be conducted in English. For questions and comments in Japanese, lecturers will provide simultaneous translation service to English.

履修条件:分子細胞生物学の基礎的知識があるとより楽しめるでしょう。
その他:この授業は英語で行いますが、日本語での質問やコメントに対しては講師が同時通訳サービスを提供します。

Grades:
To obtain credit one must attend five or more classes (of total of eight classes). Grades (A, B, C, D) will be determined based on the activity of discussion with lecturer and other students.
単位取得には8セッションのうち5つ以上に出席する必要があります.成績(A,B,C,D)は講師や他の学生との議論への参加の程度によって判定します.

Notes:
Developmental Biology 1, 2 is a discussion-based course involving critical reading of the primary literature. Each year, one of the two courses (Developmental Biology 1 or 2) will be offered, with no overlap in the material used. Taking any one of the two courses will likely give you an idea what development is about. If you wish to specialize in the field of Developmental Biology, we recommend taking all two courses.
発生生物学1, 2は原著論文をネタに議論する形式で行います.毎年2つの科目のどれか(発生生物学1または2)が開講され,これら2科目での使用論文の重複はありません.どの科目を履修しても発生生物学の「味見」はできるでしょう.自分で発生研究を志しているなら2科目全てを聞いてみることをお勧めします.

Reading lists for the previous years: 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006

 

Other courses in developmental biology

Developmental Biology I (e-learning course, in Japanese)

Developmental Biology (offered in the Department of Basic Biology)

Reproductive Biology (offered in the Department of Basic Biology)



Participating faculty:

name e-mail
SAWA Hitoshi
澤 斉

hisawa@nig.ac.jp

ZHU Yan
Yan Zhu

yanzhu@nig.ac.jp

KURAKU Shigehiro
工樂 樹洋
skuraku@nig.ac.jp
KOIDE Tsuyoshi
小出 剛

tkoide@nig.ac.jp

SAITO Kuniaki
齋藤 都暁

saitok@nig.ac.jp

ASAKAWA Kazuhide 
浅川 和秀

kasakawa@nig.ac.jp

MATSUMOTO Akihiro
松本 彰弘

aki.matsumoto@nig.ac.jp

IWASATO Takuji
岩里 琢治

tiwasato@nig.ac.jp

 


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