Developmental Biology II 2007

syllabus



Various developmental events, such as cell fate determination, cell differentiation, morphogenesis and animal behavior will be analyzed in light of gene expression, cell-cell interaction, intracellular signaling and evolution. Classes will be run by critical reading of the primary literature and discussion. It is essential that you have read the papers before coming to the class. Please download the papers from the links provided below.

This course will be run in English.

Date/Time: Friday 13:30-15:10
Location: Library 2nd floor seminar room (B201)

Course organizer: Yasushi HIROMI (NIG)

Date

Moderator

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2007/10/26

Naoyuki FUSE
Yasushi HIROMI

Morphogenesis: the Biology of Shape
Bertet C, Sulak L, Lecuit T.
Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation.
Nature 429, 667-67, 2004.@@assignment

2007/11/2

Kenta SUMIYAMA
Yasushi HIROMI

Homeotic Transformation in Mice
Depew Mj, Lufkin T, Rubenstein JLR.
Specification of jaw subdivisions by Dlx genes.
Science 298, 381-385, 2002@@assignment

2007/11/9

Kotaro KIMURA
Yasushi HIROMI

Developmental Regulation by microRNA - The beginning
Lee RC, Feinbaum RL, Ambros V.
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14.
Cell 75, 843-854, 1993.@@assignment

2007/11/16

Hiroshi SHIMIZU
Yasushi HIROMI

Positional Information
Strigini M, Cohen SM.
Wingless gradient formation in the Drosophila wing.
Current Biology 10, 293-300, 2000.

2007/11/30

Tesuji KAKUTANI
Yasushi HIROMI

Epigenetic mutations affecting development
Jacobsen SE, Meyerowitz EM.
Hypermethylated SUPERMAN epigenetic alleles in Arabidopsis
Science 277, 1100-1103, 1997 assignment

2007/12/7

Kazuo EMOTO
Yasushi HIROMI

Neuronal Polarity
de Anda FC, Pollarolo G, Da Silva JS, Camoletto PG, Feiguin F, Dotti CG.
Centrosome localization determines neuronal polarity.
Nature 436, 704-708, 2005. assignment

2007/12/21

Aya TAKAHASHI
Yasushi HIROMI

Stochasticity in Biological Process
Delattre M, Felix, AM.
Development and evolution of a variable left-right asymmetry in nematodes: the handedness of P11/P12 migration.
Developmental Biology 232, 362-371, 2001. assignment

2008/1/18

Akatsuki KIMURA
Yasushi HIROMI

Quantitative Modeling / Robustness
Barkai N, Leibler S.
Robustness in simple biochemical networks.
Nature 387, 913-917, 1997. assignment supplement

Papers can be downloaded from NIG IP addresses only. Outside students taking this course who cannot access
these papers at their home institution should contact the course organizer (yhiromi(at)lab.nig.ac.jp).

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NIG Graduate Program

NIG homepage

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last updated 2007/12/22

Copyright (c) 2004 National Institute of Genetics All rights reserved