Genome Evolution Laboratory • Kurokawa Group

Unveiling microbial community dynamics

Faculty




Research Summary

In our laboratory, we are interested in understanding about microbial genome evolution and microbial community dynamics, and we are currently reaching out in the following two major research directions; I. Facilitate the development of an integrated database “MicrobeDB.jp”, II. Microbial community dynamics. My research interests blend a background in microbial genomics and metagenomics with bioinformatics and integrated database developments that are just now allowing the prospect of illuminating microbial community dynamics. We are trying to gain a better understanding of how microbial diversity maintain as well as how it emerged.

Exploring microbial diversity in a continental serpentinite-hosted hydrothermal system.

Publications

Hori, K., Maruyama, F., Fujisawa, T., Togashi, T., Yamamoto, N., Seo, M., Sato, S., Yamada, T., Mori, H., Tajima, N., Moriyama, T., Ikeuchi, M., Watanabe, M., Wada, H., Kobayashi, K., Saito, M., Masuda, T., Sasaki-Sekimoto, Y., Mashiguchi, K., Awai, K., Shimojima, M., Masuda, S., Iwai, M., Nobusawa, T., Narise, T., Kondo, S., Saito, H1., Sato, R., Murakawa, M., Ihara, Y., Oshima-Yamada, Y., Ohtaka, K., Satoh, M., Sonobe, K., Ishii, M., Ohtani, R., Kanamori-Sato, M., Honoki, R., Miyazaki, D., Mochizuki, H., Umetsu, J., Higashi, K., Shibata, D., Kamiya, Y., Sato, N., Nakamura, Y., Tabata, S., Ida, S., Kurokawa, K., and Ohta, H. (2014). Klebsormidium flaccidum genome reveals primary factors for plant terrestrial adaptation. Nat Commun. 28, 3978.

Kato, H., Mori, H., Maruyama, F., Toyoda, A., Oshima, K., Endo, R., Fuchu, G., Miyakoshi, M., Dozono, A., Ohtsubo, Y., Nagata, Y., Hattori, M., Fujiyama, A., Kurokawa, K., and Tsuda, M. (2015). Time-series metagenomic analysis reveals robustness of soil microbiome against chemical disturbance. DNA Res. 22, 413-424.

Higashi, K., Tobe, T., Kanai, A., Uyar, E., Ishikawa, S., Suzuki, Y., Ogasawara, N., Kurokawa, K., and Oshima T. (2016). H-NS Facilitates Sequence Diversification of Horizontally Transferred DNAs during Their Integration in Host Chromosomes. PLoS Genet. 20, e1005796.