We study the evolutionary process for acquisition of novel phenotypic characters by comparative genomics and molecular evolutionary approaches, using various materials such as animals, fungi, or bacteria. Particularly, we have recently focused more on (1) Molecular evolutionary analysis of genes associated with sensory organs, (2) Evolution of septal pore cap in fungi, (3) Biodiversity and dynamics of marine microbes based on metagenomic analysis, (4) Molecular phylogeny based on mitochondrial and nuclear genes, (5) Study of disease causal gene and gene model of disease, (6) Knowledge finding and system development for big data in life science.
Molecular phylogeny of cnidarian opsin genes. We found that cnidarian opsin genes are divided into three groups and evolved independently in each lineages (class/subclass).
Yuyama I, Ishikawa M, Nozawa M, Yoshida MA, Ikeo K. Transcriptomic changes with increasing algal symbiont reveal the detailed process underlying establishment of coral-algal symbiosis. Sci Rep. 2018 Nov 14;8(1):16802.
Sultana Z, Asakura A, Kinjo S, Nozawa M, Nakano T, Ikeo K. Molecular phylogeny of ten intertidal hermit crabs of the genus Pagurus inferred from multiple mitochondrial genes, with special emphasis on the evolutionary relationship of Pagurus lanuginosus and Pagurus maculosus. Genetica. 2018 Oct;146(4-5):369-381.
Kinjo S, Monma N, Misu S, Kitamura N, Imoto J, Yoshitake K, Gojobori T, Ikeo K. Maser: one-stop platform for NGS big data from analysis to visualization. Database (Oxford). 2018 Jan 1;2018:bay027.