DDBJ (DNA Data Bank of Japan) was established in 1987 and joined international data exchange and archiving scheme between NCBI and ENA/EBI. This tripartite collaboration is called INSDC (International Nucleotide Sequence Database Collaboration).
DDBJ, as well as NCBI and EBI, is serving as one of three data inlet and outlet to the “INSD”.
DDBJ is reviewed and advised by its own advisory board and also by international advisory commitee to INSDC (panel A).
In 2009, INSDC added a collaborative meeting to deal with mass sequence data produced by the “next” generation sequencers (Sequence Read Archive) and traces produced by traditional sequencers (Trace Archive).
Daily operation of DDBJ is performed by about 10 bioannotators and system engineers under staffs’ supervision. Every year, sequence data are submitted to DDBJ by almost constant number of groups, 3,000~4000, for the last 10 years. It always consists about 10% of INSD records (panel B).
Since 1993, sequences related to patent claims are also submitted to DDBJ by Japan Patent Office because INSD is used as a framework of sequence data exchange among JPO, USTPO and EPO. In 2008, KIPO started to join this data sharing though DDBJ with help of Korean Bioinformatics Institute.
Researchers who use DDBJ to add their data in INSD have been mostly Japanese (>90% of Japanese submit the data to DDBJ), but recently researchers in neighboring countries also use DDBJ to some extent.
In 2013, DDBJ started a controlled access database, Japanese Genotype-phenotype Archive (JGA) in collaboration with JST.