Center for Genome Informatics (CGI)

Center for Genome Informatics (CGI)

Next generation sequencing (NGS) technologies have dramatically increased the throughput of DNA sequencing, and is now widely applied to various areas of life science research. Not only model organisms but all sorts of species are studied based on their nucleotide sequences through de novo sequencing/resequencing of genome, transcriptome analysis, and metagenome analysis.

In order to analyze NGS data and to obtain proper results, special knowledge and skills of bioinformatics are required in addition to knowledge of biology. CGI is engaged in the promotion of genome sciences by providing sophisticated technical support to researchers analyzing genomic data, and by developing novel bioinformatics tools and human resources.

Selected Publications

• Kinoshita-Terauchi N, Shiba K, Terauchi M, Noguchi H, Inaba K. Flagellar proteomic analysis of the brown alga Mutimo cylindricus revealed a novel calcium-binding protein abundantly localized in the anterior flagellum. Protist. 2024 Dec;175(6):126070.
• Takada K, Nakagawa S, Kryukov K, Ozawa M, Watanabe T. Metagenomic analysis of the gut microbiota of hooded cranes (Grus monacha) on the Izumi plain in Japan. FEBS Open Bio. 2024 Dec;14(12):1972-1984.
• Kaneko S, Miyoshi K, Tomuro K, Terauchi M, Tanaka R, Kondo S, Tani N, Ishiguro KI, Toyoda A, Kamikouchi A, Noguchi H, Iwasaki S, Saito K. Mettl1-dependent m7G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster. Nat Commun. 2024 Sep 24;15(1):8147.
• Fukuta K, Kato DI, Maeda J, Tsuruta A, Suzuki H, Nagano Y, Tsukamoto H, Niwa K, Terauchi M, Toyoda A, Fujiyama A, Noguchi H. Genome assembly of Genji firefly (Nipponoluciola cruciata) reveals novel luciferase-like luminescent proteins without peroxisome targeting signal. DNA Res. 2024 Apr 1;31(2):dsae006.

Center for Genome Informatics (CGI)