Database Center for Life Science (DBCLS)

Database Center for Life Science (DBCLS)

In life science, thousands of database(DB)s are publicly available worldwide, and become indispensable. However, many comments from users complaining the hard-to-use DBs suggest that these DBs and the surrounding environment are not sufficiently refined. DBCLS was established in ROIS in 2007 as a core organization of DB integration, and has been aiming to solve these issues through R&D for DB reusability, international DB standardization and various training programs. In 2023, BioData Science Initiative was established in the Joint Support-Center for Data Science Research. Under the initiative DBCLS will cooperate with the DDBJ Center and the related organizations stronger than ever. We aim to generate a synergistic effect in terms of the effective utilisation of big data.

Selected Publications

• Ikeda S, Aoki-Kinoshita KF, Chiba H, Goto S, Hosoda M, Kawashima S, Kim JD, Moriya Y, Ohta T, Ono H, Takatsuki T, Yamamoto Y, Katayama T. Expanding the concept of ID conversion in TogoID by introducing multi-semantic and label features. J Biomed Semantics. 2025 Jan 8;16(1):1.
• Hachiya T, Ishii M, Kawai Y, Khor SS, Kawashima M, Toyo-Oka L, Mitsuhashi N, Fukuda A, Kodama Y, Fujisawa T, Tokunaga K, Takagi T. The NBDC-DDBJ imputation server facilitates the use of controlled access reference panel datasets in Japan. Hum Genome Var. 2022 Dec 20;9(1):48.
• Mitsuhashi N, Toyo-Oka L, Katayama T, Kawashima M, Kawashima S, Miyazaki K, Takagi T. TogoVar: A comprehensive Japanese genetic variation database. Hum Genome Var. 2022 Dec 12;9(1):44.
• Ikeda S, Ono H, Ohta T, Chiba H, Naito Y, Moriya Y, Kawashima S, Yamamoto Y, Okamoto S, Goto S, Katayama T. TogoID: an exploratory ID converter to bridge biological datasets. Bioinformatics. 2022 Sep 2;38(17):4194-4199.

Database Center for Life Science (DBCLS)