SASAKI, Mariko

SASAKI, Mariko

Department Laboratory of Gene Quantity Biology
Job Associate Professor
Degree Ph.D. (Cornell University)
Education School of Engineering, Osaka University (B.S. in Engineering)
Graduate School of Engineering, Osaka University (M.S. in Engineering)
Weill Cornell Graduate School of Medical Sciences (a joint Ph.D. program between Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center) (Ph.D. in Molecular Biology)
Contact m_sasaki@nig.ac.jp

RESEARCH SUMMARY

We aim to understand molecular mechanisms of genomic changes that result in DNA quantity changes and how they impact cellular and organismal functions. We particularly focus on studying DNA quantity changes that involve copy number changes of repetitive sequences on the chromosome as well as production and accumulation of extrachromosomal circular DNA in budding yeast and human cells.