英語論文      日本語総説  



Imai, R., Komeda, S., Shimura, M., Tamura, S., Matsuyama, S., Nishimura, K., Rogge, R., Matsunaga, A., Hiratani, I., Takata, H., Uemura, M., Iida, Y., Yoshikawa, Y., Hansen, JC., Yamauchi, K.,  Kanemaki, MT,  Maeshima, K. (2016) Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex. Scientific Reports 6, 24712

doi: 10.1038/srep24712


Maeshima, K., Rogge, R., Tamura, S., Joti, Y., Hikima, T., Szerlong, H., Krause, C., Herman, J., DeLuca, J., Ishikawa, T., Hansen, J.C. (2016) Nucleosomal arrays self-assemble into supramolecular globular structures lacking 30-nm fibers. EMBO J.

Doi: 10.15252/embj.201592660


Maeshima, K., Ide, S., Hibino, K., Sasai, M. (2016) Liquid-like behavior of chromatin. Current Opinion in Genetics and Development. 37, 36–45

Doi: 10.1016/j.gde.2015.11.006

Liang, Z., Zickler, D., Prentiss, M., Chang. F.S., Witz, G., Maeshima, K., Kleckner, N. (2015) Chromosomes progress to metaphase in multiple discrete steps via global compaction/expansion (stress) cycles. Cell161, 1124–1137.

Kawamoto, Y., Sasaki, A., Hashiya, K., Ide, S., Bando, T., Maeshima, K., Sugiyama, H. (2015) Tandem trimer pyrrole-imidazole polyamide probes targetting 18base pairs in human telomere sequences. Chemical Science. 6, 2307-2312 DOI: 10.1039/c4sc03755c Web
Maeshima, K. Kaizu, K., Tamura, S., Nozaki, T., Kokubo, T., Takahashi, K. (2015) The physical size of transcription factors is key to transcriptional regulation in the chromatin domains. Journal of Physics: condensed matter 27, 064116 (10pp) doi:10.1088/0953-8984/27/6/064116 Web
Lab Talk Web
Maeshima, K., Nishino, Y., Joti, Y. (2014) Irregular organization in the human chromosomes revealed by X-ray scattering. SPring-8 Research Frontiers 2013 32-33 PDF
Maeshima, K., Imai, R., Hikima, T., Joti, Y. (2014) Chromatin Structures Revealed by Small-angle Xray Scattering Analysis and Computational Modeling. Methods 70, 154-161. DOI : 10.1016/j.ymeth.2014.08.008 Web
Hirata, A., Nokihara, K., Kawamoto, Y., Bando, T., Sasaki, A., Ide ,S., Maeshima, K., Kasama, T., Sugiyama, H. (2014) Structual Evaluation of Tandem, Hairpin Pyrrole-Imidazole Polyamides Recognizing Human Telomeres. Jouanal of American Chemical Society 136, 11546-11554 DOI : 10.1021/ja506058e Web
Maeshima, K., Imai, R., Tamura, S., Nozaki,T. (2014) Chromatin as dynamic 10-nm fibers. Chromosoma 123, 225-237 DOI : 10.1007/s00412-014-0460-2 Web
Nozaki, T., Imai, R., Tamura, S., Maeshima, K. (2014) Single nucleosome imaging in living human cells (Technical note,cover image) . Cytologia 79 (1) 1-2. Doi:10.1508/cytologia.79.1.1  Web
Kuga, T., Nie, H., Kazami, T., Satoh, M., Matsushita, K., Nomura, F., Maeshima, K., Nakayama, Y., Tomonaga, T. (2014) Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation. Oncogenesis 3, e94 Doi:10.1038/oncsis.2014.6 Web

Maeshima, K., Funakoshi, T., Imamoto, N. (2014) Cell-fusion method to visualize interphase nuclear pore (NPC) formation. Methods in Cell Biology, 122 239-254

Kawamoto, Y., Bando, T., Kamada, F., Li, Y., Hashiya, K., Maeshima, K., Sugiyama, H. (2013) Development of a New Method for Synthesis of Tandem Hairpin Pyrrole-Imidazole Polyamide Probes Targeting Human Telomeres. Journal of the American Chemical Society 135, 16468-16477 DOI : 10.1021/ja406737n  Web
Takata, H., Hanafusa, T., Mori, T., Shimura, M., Iida,Y., Ishikawa, K., Yoshikawa, K., Yoshikawa, Y., Maeshima, K.  (2013) Chromatin compaction protects genomic DNA from radiation damage. PLOS ONE 8, e75622 DOI : 10.1371/journal.pone.0075622 Web
Nozaki, T., Kaizu, K., Pack, C.G., Tamura, S., Tani, T., Hihara, S., Nagai, T., Takahashi, K., Maeshima, K. (2013) Flexible and dynamic nucleosome fiber in living mammalian cells. Nucleus, 4, 349-356. Doi : 10.4161/nucl.26053. Web
Shang, W. H., Hori, T., Martins, N. M., Toyoda, A, Misu, S., Monma, N., Hiratani, I.,
Maeshima, K.
, Ikeo, K., Fujiyama, A., Kimura, H., Earnshaw, W.C. Fukagawa, T.,
(2013) . Chromosome Engineering Allows the Efficient Isolation of Vertebrate
Neocentromeres. Dev Cell. 24, 635-648.
Takata, H., Matsunaga, S., Maeshima, K. (2013) The organisation of genomic DNA in mitotic chromosomes: a novel view. In Greilhuber, J., Leitch, I., Wendel, J., Dolezel, J.(Eds.), Plant Genome Diversity 2, (pp: 33-34), Springer Verlag, Germany  
Hihara, S., Pack, C. G., Kaizu, K., Tani, T., Hanafusa, T., Nozaki, T., Takemoto, S., Yoshimi, T.,  Yokota, H., Imamoto, N., Sako, Y., Kinjo, M., Takahashi, K., Nagai, T., Maeshima, K. (2012) Local Nucleosome Dynamics Facilitate Chromatin Accessibility in Living Mammalian Cells. Cell Reports 2, 1645-1656 Web
Joti, Y., Hikima, T., Nishino, Y., Kamada F., Hihara S., Takata H., Ishikawa, T., Maeshima, K. (2012) Chromosomes without a 30-nm chromatin fiber. Nucleus. 3, 404-410. PDF
Takata, H., Nishijima, H., Maeshima, K., Shibahara, K. (2012) The integrator complex is required for integrity of Cajal bodies. J Cell Sci 125, 166-175. PDF
Nishino, Y., Eltsov, M., Joti, Y., Ito, K., Takata, H., Takahashi, Y., Hihara, S., Frangakis, A.S., Imamoto, N., Ishikawa, T., Maeshima, K. (2012) Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure. EMBO J. 31, 1644-53 PDF
Takata, H., Maeshima, K. (2011) Irregular folding of nucleosomes in the cell: comment on "Cracking the chromatin code: precise rule of nucleosome positioning" by Edward N. Trifonov. Phys Life Rev 8, 51-52; discussion 69-72labpage32.html へのリンク PDF
Maeshima, K., Iino, H., Hihara, S., Imamoto, N. (2011) Nuclear size, nuclear pore number and cell cycle. Nucleus 2, 113-118. PDF
Maeshima, K., Hihara, S., Takata, H. (2010 (published in 2011)) New insight into the mitotic chromosome structure: irregular folding of nucleosome fibers without 30-nm chromatin structure. Cold Spring Harb Symp Quant Biol 75, 439-444.. PDF
Maeshima, K., Iino, H., Hihara, S., Funakoshi, T., Watanabe, A., Nishimura, M., Nakatomi, R., Yahata, K., Imamoto, F., Hashikawa, T., et al. (2010) Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase. Nat Struct Mol Biol 17, 1065-1071 PDF
Matsuyama, S., Shimura, M., Fujii, M., Maeshima, K., Yumoto, H., Mimura, H., Sano, Y., Yabashi, M., Nishino, Y., Tamasaku, K., et al. (2010) Elemental mapping of frozen hydrated cells with cryo-scanning X-ray fluorescence microscopy. X-Ray Spectrometry 39, 260-266.  PDF
Iino, H., Maeshima, K., Nakatomi, R., Kose, S., Hashikawa, T., Tachibana, T., Imamoto, N. (2010) Live imaging system for visualizing nuclear pore complex (NPC) formation during interphase in mammalian cells. Genes Cells 15, 647-660. PDF
Maeshima, K., Hihara, S., Eltsov, M. Reviw
(2010) Chromatin structure: does the 30-nm fibre exist in vivo? Curr Opin Cell Biol 22, 291-297.
Takemoto, A., Maeshima, K., Ikehara, T., Yamaguchi, K., Murayama, A., Imamura, S., Imamoto, N., Yokoyama, S., Hirano, T., Watanabe, Y., et al. (2009) The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A. Nat Struct Mol Biol 16, 1302-1308. PDF
Nishino, Y., Takahashi, Y., Imamoto, N., Ishikawa, T., Maeshima, K. (2009) Three-dimensional visualization of a human chromosome using coherent X-ray diffraction. Phys Rev Lett 102, 018101. PDF
Tahara, K., Takagi, M., Ohsugi, M., Sone, T., Nishiumi, F., Maeshima, K., Horiuchi, Y., Tokai-Nishizumi, N., Imamoto, F., Yamamoto, T., et al. (2008) Importin-beta and the small guanosine triphosphatase Ran mediate chromosome loading of the human chromokinesin Kid. J Cell Biol 180, 493-506. PDF
Eltsov, M., Maclellan, K. M., Maeshima, K., Frangakis, A. S., and Dubochet, J. (2008) Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ. Proc Natl Acad Sci U S A 105, 19732-19737 PDF
Iwai, Y., Ikeda, T., Kojima, T. M., Yamazaki, Y., Maeshima, K., Imamoto, N., Kobayashi, T., Nebiki, T., Narusawa, T., and Pokhil, G.-P. (2008) Ion irradiation in liquid of μm3 region for cell surgery. Applied Physics Letters 92, 23509 (23503 pages). PDF
Maeshima, K., Eltsov, M. (2008) Packaging the genome : the structure of mitotic chromosomes. J Biochem. 143, 145-53.  Web
Wendt, K.S., Yoshida, K., Itoh, T., Bando, M., Koch, B., Schirghuber, E., Tsutsumi, S., Nagae, G., Ishihara, K., Mishiro, T., et al. (2008). Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature 451, 796-801. PDF
Funakoshi, T., Maeshima, K., Yahata, K., Sugano, S., Imamoto, F., Imamoto, N. (2007) Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes. FEBS Lett 581, 4910-4916. PDF
Yahata, K., Maeshima, K., Sone, T., Ando, T., Okabe, M., Imamoto, N., Imamoto, F. (2007). cHS4 insulator-mediated alleviation of promoter interference during cell-based expression of tandemly associated transgenes. J Mol Biol 374, 580-590 PDF
Maeshima, K., Yahata, K., Sasaki, Y., Nakatomi, R., Tachibana, T., Hashikawa, T., Imamoto, F., Imamoto, N. (2006) Cell-cycle-dependent dynamics of nuclear pores: pore-free islands and lamins. J Cell Sci 119, 4442-4451. Web
Maeshima, K., Eltsov, M., Laemmli, U. K. (2005) Chromosome structure: improved immunolabeling for electron microscopy. Chromosoma 114, 365-375 PDF
Maeshima, K., Laemmli, U. K. (2003) A two-step scaffolding model for mitotic chromosome assembly. Dev Cell 4, 467-480. PDF
Maeshima, K., Janssen, S., Laemmli, U.K. (2001) Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides. EMBO J 20, 3218-3228. PDF


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