Developmental Biology III

発生生物学 III

発生生物学IIは,細胞運命決定,細胞分化,形態形成や個体の行動制御等の個体発生の様々な現象について,「原著論文を読んで議論する」という形式で行います.授業に参加するには与えられた論文を読んでくることが必須です.また,積極的に議論に参加することが求められます.以下のリンク先からpdfファイルをダウンロードし,読んだうえで授業に臨んで下さい.この授業は英語で行われます.

Various developmental events, such as cell fate determination, cell differentiation, morphogenesis and animal behavior will be analyzed in light of gene expression, cell-cell interaction, intracellular signaling and evolution. Classes will be run by critical reading of the primary literature and discussion. It is essential that you have read the papers before coming to the class. Please download the papers from the links provided below. This course will be run entirely in English.

Date/Time: Friday 13:30-15:10

Location: Library 2nd floor seminar room (B202)

Date

Lecturer

Topic

1.

2005/10/14

Yasushi HIROMI,
Susumu HIROSE

Timing of developmental events

Newport J, Kirschner M.
A major developmental transition in early Xenopus embryos I, II
Cell 30: 67-5686 and 687-96, 1982.
(pdf)

2.

2005/10/21

Hiroyuki SASAKI,
Noriyoshi SAKAI

Gene expression in the zygote

McGrath J, Solter D.
Completion of mouse embryogenesis requires both the maternal and paternal genomes.
Cell 37:179-183, 1984.
(pdf)

3.

2005/10/28

Yasushi HIROMI,
Ryu UEDA

Cell shape change and gene expression

Farge E.
Mechanical induction of Twist in the Drosophila Forgut/Stomodeal Primordium
Curr. Biol. 13: 1366-1377, 2003.
(pdf)

further readings and discussions

4.

2005/11/04

Toshitaka FUJISAWA,
Yasushi HIROMI

Hormones

Perego, M.
A peptide export-import control circuit modulating bacterial development regulates protein phosphatases of the phosphorelay.
PNAS 94, 8612-8617, 1997.
(pdf)

5.

2005/11/11

Yasushi HIROMI,
Noriyoshi SAKAI

Mutagenesis screen

Kile BT, Hentges KE, Clark AT, Nakamura H, Salinger AP, Liu B, Box N, Stockton DW, Johnson RL, Behringer RR, Bradley A, Justice MJ.
Functional genetic analysis of mouse chromosome 11.
Nature 425: 81-86, 2003.
(pdf)

6.

2005/11/18

Koichi KAWAKAMI,
Yasushi HIROMI

Germline development

Doitsidou M, Reichman-Fried M, Stebler J, Koprunner M, Dorries J, Meyer D, Esguerra CV, Leung T, Raz E.
Guidance of primordial germ cell migration by the chemokine SDF-1.
Cell 111: 647-59, 2002.
(pdf)

7.

2005/11/25

Yasushi HIROMI,
Yumiko SAGA

Cell fate decision and cell cycle

McConnell SK, Kaznowski CE.
Cell cycle dependence of laminar determination in developing neocortex.
Science 254: 282-5, 1991.
(pdf)
How to read this paper

8.

2005/12/02

Toshihiko SHIROISHI,
Yasushi HIROMI

Evolution of developmental patterning

Litingtung Y, Dahn RD, Li Y, Fallon JF, Chiang C.
Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.
Nature 418: 979-983, 2002.
(pdf)

ダウンロードできない等の問題がある場合には広海 (yhiromi[at]lab.nig.ac.jp) まで連絡して下さい.
If you encounter problems in downloading, please contact Yash HIROMI (yhiromi[at]lab.nig.ac.jp).

 

 

 

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last updated 2005/10/08

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