発生生物学II 2004 winter

発生生物学 II

発生生物学IIは，細胞運命決定，細胞分化，形態形成や個体の行動制御等の個体発生の様々な現象について，「原著論文を読んで議論する」という形式で行います．授業に参加するには与えられた論文を読んでくることが必須です．また，積極的に議論に参加することが求められます．以下のリンク先からpdfファイルをダウンロードし，読んだうえで授業に臨んで下さい．

　

日時：１０月１５日から毎週金曜　13:30-15:10

場所：図書館２階セミナー室（Ｂ２０2）

日程
講師
テーマ／内容

１０月１５日

広瀬進・広海健

Morphogen gradients
Driever W, Nusslein-Volhard C.
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner.
Cell 54:95-104, 1988. (pdf)

discussions

１０月２２日

上田龍・広海健

Cell lineage
Garcia-Bellido A, Santamaria P.
Developmental analysis of the wing disc in the mutant engrailed of Drosophila melanogaster.
Genetics 72:87-104, 1972. (pdf)

１０月２９日

桂勲・広海健

Cell-cell interactions
Sternberg PW, Horvitz HR.
Pattern formation during vulval development in C. elegans.
Cell 44:761-72, 1986. (pdf)

discussions

１１月０５日

酒井則良・広海健

Germline development
Brinster RL, Avarbock MR.
Germline transmission of donor haplotype following spermatogonial transplantation.
Proc Natl Acad Sci USA 91:11303-7, 1994. (pdf)
Brinster RL, Zimmermann JW.
Spermatogenesis following male germ-cell transplantation.
Proc Natl Acad Sci USA 91:11298-302, 1994. (pdf)

discussions

１１月１２日

相賀裕美子・広海健

Sex determination
Tilmann C, Capel B.
Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad.
Development 126:2883-90, 1999. (pdf)
Arango NA, Lovell-Badge R, Behringer RR.
Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development.
Cell 99:409-19, 1999. (pdf)

discussions

１１月１９日

一色孝子・広海健

Neurogenesis
Ma Q, Kintner C, Anderson DJ.
Identification of neurogenin, a vertebrate neuronal determination gene.
Cell 87:43-52, 1996. (pdf)

１１月２６日

小出剛・酒井則良

Neuronal diversity
Chaudhari N, Landin AM, Roper SD.
A metabotropic glutamate receptor variant functions as a taste receptor.
Nat Neurosci. 3:113-9, 2000. (pdf)

１２月０３日

平田たつみ・広海健

Behavior
Stowers L, Holy TE, Meister M, Dulac C, Koentges G.
Loss of sex discrimination and male-male aggression in mice deficient for TRP2.
Science 295:1493-500, 2002. (pdf) (supplementary information)

ダウンロードできない等の問題がある場合には広海 (yhiromi[at]lab.nig.ac.jp)まで連絡して下さい．

　

2004年度冬学期に開講される発生生物学IIは，すべての授業を日本語で行います．2005年に開講する発生生物学IIIではすべての授業を英語で行う予定です．

Developmental Biology II, to be offered in the winter semester of 2004, will be run in Japanese. For students who do not speak Japanese, the course organizer will offer one-hour discussion session in English for each class. To schedule a discussion session, read the asigned paper and send an email to the course organizer, listing three issues/problems that you would like to discuss. The deadline for scheduling an appointment is 13:30 of the day of the class (Friday). Indicate the time of the day that does not suit you, during the period of Saturday following the class to Friday of the next week.

Developmental Biology III, to be offered in 2005, will be run entirely in English.

　

遺伝学専攻ホームページ

遺伝研ホームページ

last updated 2004/11/08

日程	講師	テーマ／内容
１０月１５日	広瀬進・広海健	Morphogen gradients Driever W, Nusslein-Volhard C. The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54:95-104, 1988. (pdf) discussions
１０月２２日	上田龍・広海健	Cell lineage Garcia-Bellido A, Santamaria P. Developmental analysis of the wing disc in the mutant engrailed of Drosophila melanogaster. Genetics 72:87-104, 1972. (pdf)
１０月２９日	桂勲・広海健	Cell-cell interactions Sternberg PW, Horvitz HR. Pattern formation during vulval development in C. elegans. Cell 44:761-72, 1986. (pdf) discussions
１１月０５日	酒井則良・広海健	Germline development Brinster RL, Avarbock MR. Germline transmission of donor haplotype following spermatogonial transplantation. Proc Natl Acad Sci USA 91:11303-7, 1994. (pdf) Brinster RL, Zimmermann JW. Spermatogenesis following male germ-cell transplantation. Proc Natl Acad Sci USA 91:11298-302, 1994. (pdf) discussions
１１月１２日	相賀裕美子・広海健	Sex determination Tilmann C, Capel B. Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad. Development 126:2883-90, 1999. (pdf) Arango NA, Lovell-Badge R, Behringer RR. Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development. Cell 99:409-19, 1999. (pdf) discussions
１１月１９日	一色孝子・広海健	Neurogenesis Ma Q, Kintner C, Anderson DJ. Identification of neurogenin, a vertebrate neuronal determination gene. Cell 87:43-52, 1996. (pdf)
１１月２６日	小出剛・酒井則良	Neuronal diversity Chaudhari N, Landin AM, Roper SD. A metabotropic glutamate receptor variant functions as a taste receptor. Nat Neurosci. 3:113-9, 2000. (pdf)
１２月０３日	平田たつみ・広海健	Behavior Stowers L, Holy TE, Meister M, Dulac C, Koentges G. Loss of sex discrimination and male-male aggression in mice deficient for TRP2. Science 295:1493-500, 2002. (pdf) (supplementary information)