November 11, 2011 Germ-line stem cells
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Before you read these papers Generally, terminally differentiated cells are not proliferative. A multicellular organism has a stem cell system to produce a large number of terminally differentiated cells. Spermatogenesis is also maintained by germ-line stem cells. Before reading these papers, please try to define properties of a "germ-line stem cell" by yourself, and design experiments to identify the stem cell according to your definition. And then, please try to consider limitations of the method that Brinster chose. |