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Comparative Functional Genomics of the Fission Yeasts
Science(Science Express)  April 22, 2011
Niki Laboratory, Microbial Genetics Laboratory
Comparative Functional Genomics of the Fission Yeasts.
Nicholas Rhind, Zehua Chen, Moran Yassour, Dawn A. Thompson, Brian J. Haas, Naomi Habib, Ilan Wapinski, Sushmita Roy, Michael F. Lin, David I Heiman, Sarah K. Young, Kanji Furuya, Yabin Guo, Alison Pidoux, Huei Mei Chen, Barbara Robbertse, Jonathan M. Goldberg, Keita Aoki, Elizabeth H. Bayne, Aaron M. Berlin, Christopher A. Desjardins, Edward Dobbs, Livio Dukaj, Lin Fan, Michael G. FitzGerald, Courtney French, Sharvari Gujja, Klavs Hansen, Dan Keifenheim, Joshua Z. Levin, Rebecca A. Mosher, Carolin A. Müller, Jenna Pfiffner, Margaret Priest, Carsten Russ, Agata Smialowska, Peter Swoboda, Sean M. Sykes, Matthew Vaughn, Sonya Vengrova, Ryan Yoder, Qiandong Zeng, Robin Allshire, David Baulcombe, Bruce W. Birren, William Brown, Karl Ekwall, Manolis Kellis, Janet Leatherwood, Henry Levin, Hanah Margalit, Rob Martienssen, Conrad A. Nieduszynski, Joseph W. Spatafora, Nir Friedman, Jacob Z. Dalgaard, Peter Baumann, Hironori Niki, Aviv Regev, and Chad Nusbaum   
Science DOI:10.1126/science.1203357

Fission yeast is an important model for cell biology and molecular biology. Indeed the great contribution can be seen in progressing scientific fields of cell cycle, chromosome segregation, and meiosis. The genus Schizosaccharomyces of fission yeast includes only 4 species: S. pombe, S. octosporus, S. cryophilus, S. japonicus. Recently comparative genomic analyses between them have been done, led by Dr. Nick Rhind (U. Mass), and reported online in Science. Newly genomic sequencing of S. octosporus, S. cryophilus, S. japonicus have carried out by Broad Institute. An international team reveals that the fission yeasts’ genetic makeup and the activity of their genes. A team of researchers at National Institute of Genetics gives analysis of chromosomes in S. japonicus. The findings in the paper provide new, genomic tools to the community of scientists who use fission yeast, and further new insights to better understand diversity of yeast and filamentous fungi.   


fig

 Researchers compared the four known species of fission yeast, three of 
which are pictured here.